Tag Archives: Cannabinoids

Cannabinoids and Parkinson disease

This review is dedicated to research on cannabinoids and Parkinson’s disease. It summarizes some research results and what we know so far about cannabis and Parkinson’s disease. Parkinson’s disease is a progressive neurodegenerative disease, which is characterized by slow movement, rigidity of muscles, tremor at rest and loss of postural reflexes. It is a result […]

Cannabinoids: Therapeutic mechanisms

This is a short review about cannabis therapeutic usage and potential mechanisms of action.  While the endocannabinoid system is relatively new discovery some of its components are already studied and could provide insight on cannabis effects. Receptors  The main receptors identified so far are CB1 and CB2. It is known that CB1 cannabinoid receptor is […]

Cannabinoids in cancer treatment: lung and colon cancer

This short review on 2 scientific publications about cannabinoids anti-tumour effects in lung and colon cancer. Lung cancer Research team from Germany published in 2014 interesting results about cannabinoids involvement in lung cancer treatment. For their paper they have used metastatic cells from lung cancer patient and standard lung cancer cell lines to study the […]

Cannabinoids and the immune system

This is a short review of the effect of cannabinoids on immune system and more specifically on the processes of inflammation and infection. Cannabinoids are known to be able to modulate immune reaction, the brain; influence the T cells and cytokine expression (proteins involved in cell signaling and immune reactions). How was discovered the endocannabinoid […]

Cannabinoids and cancer treatment

In this review we will cover some research on cannabinoids and their anti-cancer treatment potential. THC is the main active compound in Cannabis Sativa and it mimics the effect of anandamide and 2-arachidonoylglycerol, which bind the receptors CB1 and CB2. The effect of cannabinoids on central nervous system is result of CB1 receptor activation, although […]

TLC and cannabinoid profiles

What is TLC? Thin Layer Chromatography or TLC is a popular method to determine how many components we have in our mixture. It is also used to identify a specific compound in the mixture. The components are separated based on their chemical structure, molecular weights and polarity. In order to do so it is recommended […]

Cannabis synergies: cannabinoids and terpenoids

Terpenoids are responsible for the aroma of the cannabis plant. Currently there are over 200 terpenoids. Although their yield is less than 1% in most cannabis asseys, they may represent 10% of trichome content. The most common monoterpenoids (limonene, myrcene, pinene) are lost at the rate of 5% before processing but their lost is much […]

Cannabis trichomes – structure and functions

This review is dedicated to cannabis trichomes and their structure and functions. Glandular stalked trichomes A microscope study of glandular stalked trichomes, situated on the bracts on cannabis plants shows the following correlation between trichome colour and density. It is known that glandular stalked trichomes are involved in THC production. Score Density Colour 1 Maximum […]

Cannabinoids, terpenes and fatty acids production

This research is dedicated to cannabinoids, terpenes and fatty acids production. What causes the “cannabis smell”? Cannabis plant has a specific smell and it is not results of the cannabinoids but monoterpenes and sesquiterpenes. For example, police dogs cannot smell THC but they can smell the sesquiterpene caryophyllene oxide. A smell comparison between 19 strains […]

THC synthesis and factors that affect synthesis

This research is dedicated to differences between cannabis plants producing THC and hemp plants, and factors that affect THC synthesis. What is the difference between cannabis plants that produce THC and plants that do not produce THC? Cannabis plants could produce more than 100 cannabinoids, which are mainly accumulated in female flowers (“buds”). The main […]

Chemistry and Analysis of Cannabis Terpenes

Chemistry and Analysis of Cannabis Terpenes This is a short review based on Rudolf Brenneisen’s book “Chemistry and Analysis of Phytocannabinoids and Other Cannabis Constituents” and other resources. According to the author more than 483 compounds were identified in cannabis plant, of which more than 60 cannabinoids. So far at least 66 cannabinoids have been […]

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